The Mackiewicz lab consists of modern-day explorers of the molecular world and architects of nanoscale materials. Our research is focused on the development of nanostructured materials for applications that relate to human health, the environment, and energy. Our major projects revolve around 1) the design of nanoscale materials for biomedical applications, 2) studying nanoparticle-biological interactions and nanotoxicology, 3) the development of diagnostic assays and imaging agents to monitor disease states and therapeutic response, and 4) systems for targeted drug delivery. Our long-term goal is to advance our bench side chemistry into translational applications in cancer, Alzheimer’s disease, and macular degeneration. At the same time, it is important to study the nanotoxicological effects of the new materials developed and their nanoparticle-biological interactions that will advance their designs.
Ph. D. (2005) Chemistry, Texas A&M University
B. A. (2001) Hunter College the City University of New York
B.A. (1999) Psychology, Hunter College the City University of New York
Research areasMaterials Chemistry
- Marquart, G. M. S., J.; McGill, T.J.; Kinnison, K.; Zhou, F.; Hugo, R.; Ryals, R.; Schubert, S.; Mackiewicz, M.R. The Impact of Surface Chemistry on Gold Nanorod Uptake in Stem Cell-derived Therapeutic Cells. ChemRxiv Preprint 2021. http://doi.org/10.33774/chemrxiv-2021-fhcv5
- Cunningham, B.; Engstrom, A. M.; Harper, B. J.; Harper, S. L.; Mackiewicz, M. R., Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo. Nanomaterials 2021, 11 (6), 1516.
- Marriott, L. K.; Raz Link, A.; Anitori, R. P.; Blackwell, E. A.; Blas, A.; Brock, J.; Burke, T. K.; Burrows, J. A.; Cabrera, A. P.; Helsham, D.; Liban, L. B.; Mackiewicz, M. R.; Maruyama, M.; Milligan-Myhre, K. C. A.; Panelinan, P. J. C.; Hattori-Uchima, M.; Reed, R.; Simon, B. E.; Solomon, B.; Trinidad, A. M. O.; Wyatt, L. R.; Delgado Covarrubias, A.; Zell, A.; Keller, T. E.; Morris, C.; Crespo, C. J., Supporting Biomedical Research Training for Historically Underrepresented Undergraduates Using Interprofessional, Nonformal Education Structures. JoSoTL 2021, 21 (1), 241-286.
- OSU College of Science Inclusive Excellence Award 2022
- American Chemistry Society Stanley Israel Award (2020)
- Adjunct Faculty Research Excellence Award, 2018
- Presidents Diversity Award, 2017
- Ronald McNair Mentor Award, 2014, 2015, 2016, 2017
- PSU Faculty Enhancement Travel Award, 2014
- PSU Sustainability Travel Award, 2015
- Louis Stokes Alliance for Minority Participation Mentor Award
- Ruth L. Kirschstein-NRSA (NIH) Training Grant, 2004-2005
- Industry-University Cooperative Chemistry Program (IUCCP) - Best Presenter Award, 2004
- A.E. Martell Travel Award, Texas A & M University, 2003
- MARC (Minority Access Research Center) Fellowship, 2000-2001