Jeff GautschiEducation:
B.S. California State University, Chico (1995);
Ph.D. University of California, Santa Cruz (2006);

Representative Publications:
Applying oral molecular dispersions to lead selection: a case study using a homologous series of solubility-limited compounds, Gautschi, J.T., Smithey, D.T., Choo, E., Afflerbaugh, L., Savage, S., Segraves, N., Grina, J., Rudolph, J., Ran, Y. American Association of Pharmaceutical Scientists Annual Meeting, November 2011, Poster W5231.

Evaluation of weak-base solid dispersions using the model compound dipyridamole, Smithey, D.T., Fennewald, J.C., Gautschi, J.T., Crew, M.D. American Association of Pharmaceutical Scientists Annual Meeting, November 2010, Poster AM-10-03893.

Evaluation of the polymer soluplus® for spray-dried dispersions of poorly soluble compounds, Smithey, D.T., Fennewald, J.C., Gautschi, J.T., Crew, M.D., Ali, S., Lan, Y., Langley, N. American Association of Pharmaceutical Scientists Annual Meeting, November 2010, Poster AM-10-03815.

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries, Deschamps, J.D., Gautschi, J.T., Whitman, S., Johnson, T.A., Gassner, N.C., Crews, P., Holman, T.R. Bioorganic & Medicinal Chemistry 2007, 15, 6900-6908.

Chemical investigations of a deep water marine-derived fungus: simple amino acid derivatives from an Arthrinium sp., Gautschi, J.T., Tenney, K., Compton, J., Crews, P. Natural Products Communications 2007, 2, 541-546.

Marine natural products from sponges and deep water, marine-derived fungi : Ph.D. Thesis, Gautschi, J.T. University of California, Santa Cruz: California, June 2006. [Diss. Abstr. Int., B 2006, 67, 2556.]

Localization of dysB1 to the cyanobacterial symbiont Oscillatoria spongeliae in Dysidea (Lamellodysidea) herbacea: analysis of the biosynthetic pathways and production sites for polychlorinated peptides, Flatt, P.M., Gautschi, J.T., Thacker, R.W., Crews, P., Gerwick, W.H. Marine Biology 2005, 147, 761-774.

An analysis of phakellin and oroidin structures stimulated by further study of an Agales sponge, Gautschi, J.T., Whitman, S., Holman, T.R., Crews, P. Journal of Natural Products 2004, 67, 1256-1261.

Expanding the strategies in natural product studies of marine-derived fungi: a chemical investigation of Penicilliumi obtained from deep water sediment,  Gautschi, J.T., Amagata, T., Amagata, A., Valeriote, F.A., Mooberry, S.L., Crews, P. Journal of Natural Products 2004, 67, 362-367. Erratum J. Nat. Prod. 2004, 67, 1638.

Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase, Piña, I.C., Gautschi, J.T., Wang, G.-Y.-S., Sanders, M.L., Schmitz, F.J., France, D., Cornell-Kennon, S., Sambucetti, L.C., Remiszewski, S.W., Perez, L.B., Blair, K.W., Crews, P. Journal of Organic Chemistry 2003, 68, 3866-3873.